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⚗ Evidara · Evidence Synthesis Platform

Pharmaceutical Systematic
Literature Review

From exploratory evidence scan to PRISMA-aligned,
GRADE-rated, submission-ready analysis.

⚡ Rapid Evidence Scan 🔬 Full Systematic Review
60–90 seconds · Exploratory · Not for submission
~15–20 minutes · PRISMA 2020 · GRADE · FAERS signals
Real deterministic run · semaglutide / cardiovascular outcomes · Jul 2026
124 Identified
→
111 Screened
→
41 Included
RCT evidence pool graded GRADE High ⊕⊕⊕⊕ · 19 studies, 0 downgrade factors · SR/MA Moderate, observational Very Low. Live sources update, so a re-run will differ slightly.
Two Pathways

Choose your evidence depth

Rapid exploration or PRISMA-aligned systematic review — both built on the same evidence infrastructure.

⚡ Free · No signup required

Rapid Evidence Scan

60–90s
Automated abstract screening (PubMed, Europe PMC, ClinicalTrials.gov)
AI-assisted PICO extraction
Key findings summary with evidence gaps noted
PMID citations on every finding
Immediate output — no queue, no wait
Not GRADE rated per outcome
Not for regulatory or HTA submission
FAERS signals not included
Title & abstract only — full text not accessed except open-access (PMC)

Good for: scoping, advisory board prep, grant applications, investor narrative, hypothesis generation

⚡ Start Rapid Scan →

Full Systematic Review

15–20 min
PRISMA 2020-aligned reporting
GRADE certainty scaffold per study design pool — requires human methodologist validation
FAERS adverse event signal analysis with ROR
16-database parallel retrieval + deduplication
21 CFR Part 11-inspired audit trail (not validated software — human review required before regulatory submission)
Every finding traces to PMID, NCT ID, or FAERS
Human review required before any submission use
Title & abstract only — full text not accessed except open-access (PMC)

For: HTA preparation, payer dossier support, regulatory evidence, publication planning

Who It's For

Built for the evidence lifecycle

Each team has a specific evidence challenge. Evidara is designed to address it directly.

Medical Affairs

Evidence on Demand

Challenge

Evidence synthesis for payer and KOL engagement typically takes weeks of analyst time and significant budget.

Solution

Rapid Scan in 60–90s for meeting prep. Full SLR chain as the foundation for evidence briefs. Same platform, two speeds — one decision workflow.

SLR-W SLR P · Payer
Market Access / HEOR

HTA-Oriented Evidence

Challenge

HTA submissions require PRISMA-aligned evidence with GRADE quality ratings — a manual process that takes months.

Solution

Full SLR chain designed for PRISMA 2020 methodology. GRADE applied per outcome. FAERS signals included. Full audit trail on every run.

SLR HEOR D · Discovery
Regulatory Affairs

Benefit-Risk Evidence

Challenge

Benefit-risk frameworks require systematic evidence across all relevant published literature — manually intractable at scale.

Solution

Chain Reg and Chain SLR combined. 21 CFR Part 11-inspired audit trail (not validated software). Human review declaration required before export. Association never presented as causation.

Reg SLR C · Safety
How It Works

Five stages from query to evidence

Click any stage to see exactly what happens. No black boxes.

Output Standards

What every output includes

The same standards apply to every run. No exceptions. No overrides.

Explicit PICO statement
Population, Intervention, Comparator, Outcome declared before any search runs — shown to you for review.
Verbatim search strings logged
Exact query strings recorded for each database — suitable for inclusion in a methods section.
Source provenance on every finding
Every numerical result, endpoint, and signal links to a PMID, NCT ID, or FAERS case number.
Evidence classification on every claim
Each finding is labelled: Descriptive · Associative · Causal Hypothesis. Association is never presented as causation.
Evidence gaps explicitly documented
Gaps in the literature are surfaced and noted — not suppressed or filled with inference.
Evidence gaps and limitations explicitly documented
Where studies contradict each other, both findings are shown. Evidence gaps and methodological limitations are documented, not hidden.
GRADE quality assessment per outcome Full SLR only
Certainty rated: High · Moderate · Low · Very Low — per primary outcome, with rationale.
FAERS signal analysis with ROR Full SLR only
Reporting Odds Ratio calculated. Signal classified: Detected · Weak · Not Detected. Under-reporting assumption always stated.
21 CFR Part 11-inspired audit trail Full SLR only
Immutable run log with agent steps, model versions, retrieval queries, and timestamps.
Governance notice on every export
Human review declaration required — user must confirm review before export is enabled. Not a replacement for qualified expert judgment.
Compliance Framework

Built to the standards that matter

Every run governed by the same framework — no exceptions, no overrides, no shortcuts.

PRISMA 2020
GRADE
FAERS
21 CFR Part 11
HIPAA
GDPR Art. 9
EU AI Act Art. 9–15

Every claim carries a PMID, NCT ID, or FAERS reference. Association is never upgraded to causation. Human review required before any output is used for submission purposes.

Ready to run your first evidence review?

Rapid Scan is free — no signup required. Full SLR available on the platform.

⚡ Start Rapid Scan — Free →