Pricing Platform Skills Contact
Evidara Chat

Ask the evidence. Get an answer you can defend.

Pose any clinical, safety, or competitive question in plain language. Evidara searches the primary literature, reads it, and answers — from what it retrieved, flagging any claim it cannot source. An evidence engine, not a chatbot.

Grounded in PubMed · ClinicalTrials.gov · openFDA FAERS · Europe PMC — every citation traceable to a PMID, NCT or FAERS record
evidarabio.com / chat
What's the efficacy and safety evidence for resmetirom in MASH?
🔎 Searching PubMed: resmetirom MASH efficacy → 8 sources ✓ Reading abstracts & trial records · cross-checking FAERS

Resmetirom (a liver-directed THR-β agonist) showed significant histologic benefit in MASH: the pivotal phase 3 trial reported higher rates of NASH resolution and ≥1-stage fibrosis improvement vs placebo at 52 weeks PMID 38324483.

Safety was generally manageable; the most common signals were diarrhea and nausea, with FAERS surveillance consistent with the trial profile FAERS. Long-term outcome data remain limited NCT03900429.

S12024 · PMID 38324483
A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis
VerifiedRCT
S2NCT03900429
MAESTRO-NASH — phase 3 resmetirom outcomes study (active, not recruiting)
VerifiedTrial registry
Certainty of evidence High ⊕⊕⊕⊕ Automated
Assigned by a deterministic rule-based scaffold from abstract-level signals, not by a methodologist with full texts — a starting point for expert review, not a finished assessment.
Illustrative — your answers stream live, with real current citations and their own certainty rating.
Reads from the primary record PubMedClinicalTrials.govopenFDA FAERSEurope PMCOpenAlex
How it works

From a plain-language question to a cited answer.

You watch it work — every search and source is shown, so the answer is auditable, not a black box.

You ask
"resmetirom MASH efficacy?"
PubMedTrialsFAERS
Evidara reads
retrieves & synthesizes
Cited answer
claim → PMID 38324483
01

Ask naturally

Type a question the way you'd ask a colleague — a drug, an indication, a competitor, a safety signal.

02

It searches

Evidara translates your question into expert literature queries and pulls live results from PubMed, trials, and FAERS.

03

It reads & reasons

It reads the retrieved evidence and synthesizes an answer grounded only in what it found — so it can't make claims up.

04

You get cited proof

Every citation links to a PMID, NCT, or FAERS record — ready to verify, export, or defend to MLR.

What it can do

One chat for the whole evidence workflow.

🔎

Live literature search

Asks PubMed, Europe PMC, and ClinicalTrials.gov in real time and ranks what matters — no manual searching.

📎

A citation per claim

Every statement carries a PMID / NCT / FAERS source, each identifier checked against the source API and labelled verified or not. Identifiers the model wrote that we didn't supply are flagged, never passed off as citations.

🛡️

Safety on demand

Pull FAERS adverse-event signals for any drug and have them interpreted alongside the trial evidence.

⚔️

Competitive landscape

Ask who's in a space and where the gaps are — pipeline, trials, and positioning, grounded in the record.

▶️

One-tap deep analysis

When a question deserves a full brief, launch a complete SLR, CI, payer, or regulatory chain in one click.

🔗

Save & share

Drop key papers into an Evidence Basket — Impact-scored and GRADE-tagged — or share an answer as a public link.

Built for your team

One chat, every evidence role.

The same grounded engine, tuned to how each function actually works.

MA

Medical Affairs

Prep KOL engagements and congress with the latest evidence and cited, PMID-backed objection-handlers.

MX

Market Access & HEOR

Build payer value narratives and answer evidence questions with traceable, defensible proof.

CI

Competitive Intelligence

Track the landscape and surface gaps — pipeline, trials, and positioning, grounded in the record.

R&D

Clinical & Research

Run a rapid evidence scan or launch a full systematic review without ever leaving the chat.

Why it's different

A generic chatbot guesses. Evidara retrieves.

  • Grounded, not generative. Answers come only from evidence it actually retrieved this turn.
  • Traceable. Every citation is a stable identifier you can open and check.
  • Honest about limits. It flags gaps, sparse data, and where human expert review is required.
  • Built for regulated work. Auditable, exportable, and designed for MLR-grade defensibility.
Evidara Chat
Generic AI — confident, source-free answers
Citations you can open — unverified claims flagged
Trained on a frozen snapshot
Searches the live literature each time
Can't show its work
Shows every search and source
Hallucinates citations
Won't claim beyond what it retrieved
FAQ

Questions, answered.

What sources does it search?

PubMed, Europe PMC, and ClinicalTrials.gov for literature and trials, plus openFDA FAERS for post-market safety, and OpenAlex for the scholarly graph — queried live, every time.

Does it make up citations?

No. Citations are rebuilt from the evidence actually retrieved that turn — an identifier the model writes itself is stripped and flagged as unverified, never promoted to a citation. Claims it cannot source are flagged rather than hidden, and human review is required before external use.

Can it run a full systematic review or competitive brief?

Yes — when a question warrants it, the chat surfaces a one-tap launch into a complete analysis chain (SLR, competitive intelligence, payer, regulatory, and more).

Is it safe for regulated, MLR-reviewed work?

It's built for it: auditable searches, traceable citations, explicit limitation flags, and a human-review requirement before any clinical, regulatory, or investment use.

Ask your first question.

Evidence-grade answers in minutes — every unverified claim flagged. See what your literature actually says.

Start chatting — free →